Scotland are six points behind the visitors, having lost three in a row since beating the Welsh on the opening weekend.
"This weekend is about finishing on a high," said head coach Bryan Easson. "It's about everything coming together post some really good performances and some really difficult stages in games.
"We've learned a lot about ourselves and now have an opportunity to put together those learnings on the pitch."
Scotland finished one point in the table behind the Irish in 2024, losing 15-12 in Belfast.
"Ireland are a very physical side and we have to fight fire with fire," added Easson. "I see it being tight - last year was a difficult one for us to take.
"We believe we can put Ireland under pressure if we get our processes right."
Scotland open their World Cup campaign against Wales in late August and will also meet Fiji and Canada, with matches taking place in Manchester and Exeter.
"We don't have long before we come back in for World Cup preparation," said Easson.
"I think we're on track. We've capped seven players in this Six Nations, we're working hard on growing the base around the squad."