De Bruyne's final home game will come against Bournemouth on 20 May, with away matches to play at Southampton and Fulham.
And he can ensure a dream ending if City beat Crystal Palace in the FA Cup final at Wembley.
"Maybe he is still good enough to play here," said former Manchester City defender Micah Richards.
"Maybe he hasn't the press, but quality - he believes he can still play at the top level. He has said he is playing injury-free now.
"Age catches up though with you, and your body can't do what you want to do. But he keeps the ball and his football intelligence is still there. He is telling the club 'I can still play at this level'.
"I am talking as a fan, and I am a fan of KDB. Something in me just says 'one more year' - he can still do it. Maybe it is just a business decision."
Does Richards have a point?
De Bruyne has scored 30 Premier League goals since turning 30 years old, with Sergio Aguero and Yaya Toure the only players to score more for City with 41 apiece.
He became the first player since the great Lionel Messi to register 250 goal involvements under Guardiola, with 92 goals and 158 assists in nine seasons.
Meanwhile, Wolves will be glad to see the back of De Bruyne as the midfielder has now scored six goals and provided five assists in 11 league games against them.
But over the past two seasons, the Belgian has made just 43 Premier League appearances because of a series of injuries.
Former Liverpool defender Jamie Carragher said De Bruyne is still "levels above the elite players in the world", adding: "He doesn't think he has finished at the top level.
"He still thinks he can play at the top level of European football. I thought maybe he would go to Saudi Arabia or America, but after hearing him speak, it sounds like he isn't ready for that.
"He is one of the highest-paid players in world football and has been injured a lot. It has been hard to justify giving him a new deal from a business point of view. He is still a star player but he is not going to play every week.
"Let's talk about the statue - for me he is Manchester City's greatest ever player."